The Claret and Blue lost to Chelsea in the FA Cup final of that year and they will hope to avoid the men from Stamford Bridge at all costs in knock-out football this year.
Also in the hat for the quarter-finals are Manchester rivals United and City, as well as Arsene Wenger's Arsenal.
Tottenham Hotspur, Portsmouth and Blackburn Rovers complete what is an established looking line-up.
Martin O'Neill will be desperate for a home draw as Villa narrowly survived at Sunderland in the fourth round and he knows that the backing of the home faithful can make all the difference.
The Claret and Blue have no reason to fear anyone in the competition but, even so, the road to Wembley is unlikely to be a smooth one.